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A Comparison Study of Cerebral Cortical Activity at Chronic Stroke Patients According to Differences in Frequency of Repetitive Transcranial Magnetic Stimulation: Randomized Controlled Trial

Journal of Magnetics, Volume 28, Number 4, 31 Dec 2023, Pages 507-513
Jung-Woo Jeong (Bobath Memorial Hospital), Byung-Il Yang * (Sangji University), Bo-Kyoung Song * (Kangwon National University)
Abstract
This study aimed to characterize the cerebral cortical activity of chronic stroke patients according to differences
in frequency of repetitive transcranial magnetic stimulation (rTMS). 20 chronic stroke patients were
treated with 5 Hz high-frequency rTMS group (HFG) applied to the cerebral cortex on the damaged side and 1
Hz low-frequency rTMS group (LFG) applied to the cerebral cortex on the non-damaged side. The activity of
the cerebral cortex was examined using electroencephalography (EEG) to changes in alpha waves (α-wave) and
sensorimotor rhythm (SMR) wave. As a result, in two groups, HFG showed a significant difference in F3 and
P4 for α-wave and in F3 and F4 for SMR wave (p<0.05) (p<0.05). In LFG, there was no significant difference in
α-wave, but SMR wave showed a significant difference in F4 (p>0.05) (p<0.05). And in the comparison between
two groups, α-wave showed a significant difference in F3 (p<0.05). SMR wave showed no significant difference
(p>0.05). Through this, it is judged that 5 Hz high-frequency rTMS has a positive effect on cerebral cortical
activity in chronic stroke patients compared to 1 Hz low-frequency rTMS.
Keywords: high frequency repetitive transcranial magnetic stimulation; low frequency repetitive transcranial magnetic stimulation; stroke; electroencephalography; sensorimotor rhythm wave
DOI: https://doi.org/10.4283/JMAG.2023.28.4.507
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