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A Comparative Study of 5 Hz Repetitive Transcranial Magnetic Stimulation on Cortical Activity and Upper Limb Function in Chronic Stroke Patients with Different Stroke Etiologies: A Case Study

Journal of Magnetics, Volume 27, Number 4, 31 Dec 2022, Pages 506-513
Jung-Woo Jeong (Bobath Memorial Hospital), Byung-Il Yang * (Sangji University), Bo-Kyoung Song * (Kangwon National University)
Abstract
The purpose of this study was to investigate the effect of 5Hz repetitive transcranial magnetic stimulation
(rTMS) on cortical activity and upper limb function in the etiology of chronic stroke patients. 2 patients with
ischemic stroke and 2 patients with hemorrhagic stroke who satisfied the selection criteria were selected using
the ABA’ single subjective design. The study period was applied 18 times in all 4 patients: 3 times at baseline
(A), 12 times in intervention period (B), and 3 times in baseline (A'). During intervention period(B), 5Hz rTMS
was applied 4 times a week for 3 weeks, and no intervention was performed during the 3 baseline (A) and baselines
(A’). Electroencephalography (EEG), box and block test (BBT), and fugl-meyer assessment (FMA) were
performed to investigate changes in cortical activity and upper limb function. As a result, EEG and BBT were
changed after intervention (B) in ischemic stroke patients than in hemorrhagic stroke patients, and there was
no difference in FMA of all stroke patients. Through this, it is thought that 5 Hz r TMS can help to improve
cortical activity and upper limb function in ischemic stroke rather than hemorrhagic stroke.
Keywords: repetitive transcranial magnetic stimulation; ischemic stroke, hemorrhagic stroke; cortical activity, upper limb function
DOI: https://doi.org/10.4283/JMAG.2022.27.4.506
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