Newborns and premature infants generally undergo brain MRI tests under sedation and anesthesia. Sedation
or anesthesia has a risk of side effects and may be contraindicated in newborns or premature infants with congenital
diseases. Therefore, this study tested subjects by applying a self-sleep induction method. This study compared
and analyzed a group (Group A), which tested 42 subjects using a sedation method (used chloral hydrate
or Midazolam) for the brain MRI examination, and a group (Group B), which tested 84 subjects under selfsleep
induction by applying a wrapping after feeding technique using a vacuum splint (MedVac). For image
analysis, this study conducted SNR analysis between the two groups, calculated Cohen's Kappa coefficient to
test the a greement b etween o bservers, and analyzed the e xamination t ime to e valuate the efficiency o f the
examination. The results of image analysis (SPSS independent sample t-test) were evaluated as T1 (p=0.101)
and T2 (p=0.319), and the inter-observer agreement test (p=0.075) and statistical analysis of test time (p=0.160)
were also statistically significant. There was no difference. Brain MRI through sleep induction is considered a
safe and efficient test method.