Based on the fact that it is difficult to extract pure radioactive isotopes during the manufacturing process of the
radioisotope, we conducted a study on the purity of 131I used in patients in clinical practice. Nuclear medicine
treatment using 131I is performed by being admitted to a dedicated ward. In the most commonly used method
for producing 131I, 129I is present in 0.1 %. Therefore, the importance of the management of pipes arises.
According to the calculation formula, in the case of 131I, the radioactivity does not increase after 60 days. However,
if 129I is present in 0.1 %, the radioactivity increases after 6 months. A similar result was also obtained
when the pipes in the treatment room used for 8 years were measured. Therefore, the development of a pure
131I generation method is currently required, and a realistic radiation safety management system such as applying
the extraction technology of 129I or enacting the regulations for the follow-up management of sealed pipes
should be constructed as auxiliary methods.