본 연구는 임상에서 적용되는 반복 경두개 자기 자극(repetitive transcranial magnetic stimulation, rTMS)의 구체적인 적용법을
알아보고자 하였다. rTMS는 저빈도 rTMS(low frequency, LF-rTMS), 고빈도 rTMS(high frequency, HF-rTMS), 세타 버스트 자
극(theta burst stimulation, TBS), 쌍연관 자극(paired associative stimulation, PAS)의 4가지 방법으로 적용하여 사용할 수 있다.
LF-rTMS와 continuous TBS(cTBS)는 대뇌피질의 흥분성을 억제하고 HF-rTMS와 intermittent TBS(iTBS)는 대뇌피질의 흥분성을
증가시키는 방법으로 사용되며 PAS는 구심성 감각 정보에 대한 자극과 r TM S 사이 가격에 따라 흥분성을 억제하거나 증가하는
방법이다. 본 연구에서 제시된 4가지 r TM S 적용법을 이해하고 임상에서 활용 근거로 사용되기를 기대한다.

The purpose of this study was to find out how to apply repetitive transcranial magnetic stimulation (rTMS) for neurological
condition in clinical practice. Repetitive transcranial magnetic stimulation (rTMS) can be largely applied in four rTMS protocol: low
frequency rTMS (LF-rTMS), high frequency rTMS (HF-rTMS), theta burst stimulation (TBS), and paired associative stimulation
(PAS). Specifically, LF-rTMS and continuous TBS (cTBS) are methods of suppressing the excitability of the cerebral cortex, and HFrTMS
and intermittent TBS (iTBS) are used as methods of increasing the excitability of the cortex. PAS is being introduced as a
method in which excitability can be suppressed or increased depending on the price between stimulation for afferent information and
stimulation for TMS. In addition, rTMS can be used in combination with residual effects and other protocol depending on the
differences in applied methods. Further research will have to be explained by including effects such as differences in the number and
intensity of stimulation used in the rTMS clinical application. Through the four clinical applications of rTMS presented in this study, it
is expected to be used as a basis for future TMS protocol.