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Home > Issues > SearchAssessment the Influencing Factors on MRS Signal Obtained from High Magnetic Field Strength (1.5T) MRI Scanners During the Application of Homemade Metabolite Phantom
Journal of Magnetics, Volume 24, Number 1, 31 Mar 2019, Pages 90-98
Mahdi Saeedi-Moghadam (Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University), Majid Pouladian * 
(Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University), Mehrzad Lotfi (Medical Imaging Research Center, Shiraz University of Medical Sciences), Reza Faghihi (Department of Nuclear Engineering, School of Mechanical Engineering, Shiraz University)
(Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University), Mehrzad Lotfi (Medical Imaging Research Center, Shiraz University of Medical Sciences), Reza Faghihi (Department of Nuclear Engineering, School of Mechanical Engineering, Shiraz University)
Abstract
Purpose: This study aimed to present a protocol for constructing MRS phantoms that are supposed to be subjective of spectroscopy using 1.5T machines. Methods: As phantom containers, laboratory clear/amber glass
bottles and an internally-designed Plexiglass and PVC cylinders were tested to evaluate the effect of phantom material and design on produced signals. HPLC and distilled-water were evaluated as solvent of metabolites.
Finally, a protocol was suggested. Results: The results revealed that the physical walls of internally-designed phantom affect the WS and its baseline noise. The results also showed that even the amber-pigments inside the bottles can affect the MRS signal. Accordingly, the combination of HPLC-water inside clear-glass containers is suggested. Conclusion: The suggested protocol is as follows, apply clear-glass container as phantom body, do not build internal-structures using physical walls of glass or any other materials. Apply HPLC-water as solvent instead of distilled-water. Check the purity of chemical metabolites.
bottles and an internally-designed Plexiglass and PVC cylinders were tested to evaluate the effect of phantom material and design on produced signals. HPLC and distilled-water were evaluated as solvent of metabolites.
Finally, a protocol was suggested. Results: The results revealed that the physical walls of internally-designed phantom affect the WS and its baseline noise. The results also showed that even the amber-pigments inside the bottles can affect the MRS signal. Accordingly, the combination of HPLC-water inside clear-glass containers is suggested. Conclusion: The suggested protocol is as follows, apply clear-glass container as phantom body, do not build internal-structures using physical walls of glass or any other materials. Apply HPLC-water as solvent instead of distilled-water. Check the purity of chemical metabolites.
Keywords: MRS; phantom material; phantom structure
DOI: https://doi.org/10.4283/JMAG.2019.24.1.090
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