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Effect of Pulsed Magnetic Field on Red Blood Cell Aggregation: Mobility

Journal of Magnetics, Volume 23, Number 2, 30 Jun 2018, Pages 318-322
Hyun Sook Lee * (Department of Oriental Biomedical Engineering, Sangji University), Jaekwon Sim (Department of Oriental Biomedical Engineering, Sangji University), Hyeji Park (Department of Oriental Biomedical Engineering, Sangji University), Do Gwun Hwang (Department of Oriental Biomedical Engineering, Sangji University)
Abstract
The disaggregation and displacement of stacked red blood cell (RBC) are known to be dependent on the electric state of hemoglobin and the strength and gradient of external magnetic field. The present study has been
investigated the dependence of the change in aggregation and mobility of RBCs on the intensity and time duration of pulsed magnetic field (PMF), in addition to stimulus area. The magnetic field intensities are 0.07, 0.19,
and 0.27 T, pulse time of 0.102 ms and pulse repetition rate was 1 Hz. Live blood analysis was used in order to quantitatively estimate the mobility and morphology of RBC exposed to PMF stimulus. The optimal time and
intensity of PMF stimulus were 10 minutes and 0.27 T. The difference in the stimulus area did not show much. The continuance of the effect of PMF stimulus was observed to be 2 hours. Also it was verified the movement of the RBCs was accelerated for steady exposure of PMF stimulus. In order to identify a link between disaggregation in rouleau-formed RBCs and PMF stimulus, it is necessary to investigate the correlation between PMF
intensity and the stimulus time, the mobility of RBCs, and the number of stacked RBCs.
 
Keywords: Pulse Magnetic Field; Red Blood Cells; Aggregation; Magnetic Stimulus; Rouleau formation
DOI: https://doi.org/10.4283/JMAG.2018.23.2.318
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