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No.1(pp.1-34)

Home > Issues > Volume 13 (2008) > No.1(pp.1-34)

Detection of Magnetic Nanoparticles and Fe-hemoglobin inside Red Blood Cells by Using a Highly Sensitive Spin Valve Device

Journal of Magnetics, Volume 13, Number 1, 31 Mar 2008, Pages 30-33

Sang-Hyun Park(School of Physics and Astronomy, Seoul National University), Kwang-Sup Soh(School of Physics and Astronomy, Seoul National University), Do-Guwn Hwang(Department of Oriental Biomedical Engineering, Sangji University), Jang-Roh Rhee(Department of Physics, Sookmyung Women's University), Sang-Suk Lee*

(Department of Oriental Biomedical Engineering, Sangji University)

Abstract

A highly sensitive, giant magnetoresistance-spin valve (GMR-SV) biosensing device with high linearity and very low hysteresis was fabricated by photolithography. The detection of magnetic nanoparticles and Fe-hemoglobin inside red blood cells using the GMR-SV biosensing device was investigated. When a sensing current of 1 mA was applied to the current electrode in the patterned active devices with an area of 2×6 μm², the output signals were about 13.35 mV. The signal from even one drop of human blood and nanoparticles in distilled water was sufficient for their detection and analysis.

Keywords: magnetic nanoparticles; Fe-hemoglobin; giant magnetoresistance-spin valve (GMR-SV); biosensor

DOI: 10.4283/JMAG.2008.13.1.30

Full Text: PDF

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