The purpose of this study is to figure out how uptake counts of technetium (^99mTc) among radioisotopes in the human body are affected if computed tomography (CT), magnetic resonance imaging (MRI) and isotope examination are performed consecutively. ^99mTc isotope material, iodinated contrast media for CT and paramagnetic contrast media for magnetic resonance (MR) were used as experimental materials. First, ^99mTc was added to 4 cc normal saline in a test tube. Then, 2 cc of CT contrast media such as Iopamidol^® and Dotarem^® were diluted with 2 cc normal saline, and 2cc of MRI contrast media such as Primovist^® and Gadovist^® were diluted with 2 cc normal saline. Each distributed contrast media was a total of 4 cc and included 10m Ci of ^99mTc. A gamma camera, a LEHR (Low energy high resolution) collimator and a pin-hole collimator were used for image acquisition. Image acquisition was repeated a total of 6 times and 120 frames were obtained and uptake counts of ^99mTc were measured (from this procedure). In this study, as a result of measuring the uptake counts of ^99mTc using the LEHR collimator, the uptake counts were less measured in all contrast media than normal saline as a reference. In particular, the lowest uptake counts were measured when Gadovist^®, contrast media for MRI, was used. However, the result of measuring the uptake counts of ^99mTc using the pin-hole collimator showed higher uptake counts in all contrast media, except for Iopamidol^®, than normal saline as a reference. The highest uptake counts were measured particularly when Primovist^®, contrast media for MRI, was used. In performing the gamma camera examination using contrast media and ^99mTc, it is considered significant to check the changes in the uptake counts to improve various diagnosis values.